عنب انگور است و او بانجیر ماننده است، و آنکه سخت شیرین
بود گرم و نرم است شکم فراز آرد، و تن را فربه گرداند، و ذکر قوی کند، و آنکه تنک[1454]
بود زودتر بگوارد، و نفخ کمتر کند و آنکه هنوز ترش باشد مزاجش سرد و خشک است، شکم ببندد،
و سپیدش گرمی کمتر دارد و اندر او نفخ است، و نیز اندر او جنسی است که گرمی او عظیم
است، و باشد که سکته آرد و باشد که بکشد و اندر امرود همچنین جنسی قتّال است نیز و
حصرم (غوره)[1455] سرد
و خشک است، شکم ببندد صفرابشکند و خون بنشاند، و زبیب[1456] برحسب مزاج انگور است آنکه
از او گرفته بوند و غذاش هم چون غذای اصلش بود بکمی و بیشی، و هرچه بگوشت به بود وی
شیرین‌تر بود گرم‌مزاج باشد، و غذای بسیار دهد، سینه و شش را سود کند که اندر او رطوبتی
بود غلیظ، و آن جنس اوی که گوشت کمتر دارد حرارتش کمتر و اندک بود، و معده قوی گرداند،
و طبیعت ببندد، و کسی که خواهد که طبیعتش نرم شود آن خورد که بگوشت تر[1457] بود و
شیرین‌تر دانه از وی جدا کرده، و گر آبش پخته بخورند طبیعت نرم کند بیشتر، همچنانکه
آب انگور قویتر است بنرم کردن طبیعت که جرمش، و هرکه خواهد که طبیعتش بسته بود آن بی‌گوشت
را خورد با دانه، و پیشینگان گفته‌اند که اندر هر ماهی هرکه هفت روز بهر بامدادی هفت
مثقال میویز بخورد وی از هر علّت که از طبع خیزد ایمن باشد، و حفظش نیک شود، و ربّ
حصرم سرد و خشک است، صفرا بشکند تشنگی بنشاند و قی ببرد و طبیعت ببندد، و میپخته سعال
را نیک باشد و درد کلی و مثانه را، و کشمش معتدل است قوّتش بقوّت میویز ماند، لیکن
از او لطیفتر و گرمتر است بطبع و اندر او نیز نفخ اندکست.
ابنیه
///////////////
حصرم. بپارسی غوره است و بلفظی دیگر کجب و کجم نیز خوانند و طبیعت
وی سرد است در اول و خشک است در دویم و گویند سرد است در دویم و خشک است در سئوم و
چنین گویند سرد است در اول و خشک است در سئوم جهت دفع صفرا بغایت نافع بود و حرارت
بشکند و معده و جگر را نافع بود اما مولد ریاح و مغص بود و شکم ببندد و مصلح وی گلنگبین
بود و صاحب تقویم گوید مضر بود بآلات تناسل و منی و مصلح آن انیسون و عسل بود و بدل
آن ریباس یا حماض اترج بود
اختیارات بدیعی
///////////
غوره، حصرم
Sour grapes
به فارسی غوره نامند؛ انگور خام نارس سبز ترش است هر نوع
که انگور باشد.
طبیعت آن در اول دوم سرد و در آخر آن خشک و عصارۀ آن سردتر
و خشک‌تر از آن تا سوم
خواص: فشارخون را تعدیل و صفرا را پائین آورده و بلغم معده
را از بین می برد. طبع را بند می آورد و مقوی کبد و بدن و رافع تشنگی و سستی اعضاء
می باشد. ضماد سائیده خشک آن جهت خوشبو کردن عرق بدن است. جوشش خون و خارش و سستی بدن
را از بین برده و برای معده سرد ضعیف کننده و نفاخ و دل پیچه به وجود می آورد. در بعضی
از مزاج ها ایجاد عطش نموده و از تهوع جلوگیری می نماید مصلح آن گل قند و انیسون و
انجیر است
رب آن تشنگی را برطرف می کند و حرارت را تسکین داده و التهاب
معده را رفع و اسهال سوداوی را بند آورده و اشتهاآور است. حافظ جنین و مقوی احشاء است
و خمار را از بین می برد و برای سینه مضر و مصلح آن گل قند و شربت خشخاش است.
مخزن الادویه، تألیف مرحوم سید محمد حسین عقیلی علوی خراسانی
شیرازی
///////////
آبغوره یا آب غوره عصارهٔ غوره است که برای طعم دادن و ترش کردن غذا به کار می‌رود..
ویکی
/////////////
به عربی:
الفيرجوس (بالإنجليزية: Verjuice) هو عصير حامض مصنوع من بعض أنواع العنب أو من الحصرم. ويهو شراب يتسعمل
بشكل واسع في المطبخ السوري. حيث كانت تعده السيدات من العنب المزروع في المزارع.
////////////
به ترکی آذری آبغوره:
Abqora – Kal üzümdən alınmış üzüm meyvəsinin
şirəsi, qorasuyu.
///////////
به ترکی استانبولی کوروک (غوره) سویو (آب)
Koruk
suyu olgunlaşmamış üzümleri ezip suyunu çıkartarak elde dilen oldukça ekşi,
asitli bir içecektir. Ortaçağ Avrupası'nda, özellikle de Batı Avrupa'da en
yaygın içeceklerden biri olan koruk suyu, o dönemde eski Fransızcadaki biçimi
ile vertjus olarak anılmıştır. Çoğu zaman tadını değiştirmek için içine limon
ve çeşitli baharatlar atılır.
Günümüzde
ana yemekler içinde kullanımını şarap ve sirkeye bırakmışsa da Ortaçağ
Avrupası'nda aşçıların en sık başvurduğu tatlandırıcı olmuştur. Bugün sadece
bazı aşçıların salata süsleme amacıyla limon yerine kullandığı koruk suyu
Fransız mutfağında hâlâ bilinen ve kullanılan bir tatlandırıcıdır.
////////////////
به آفریکانس، آلمانی، اسپانپولی، فنلاندی، ایو، فرانسه،
هلندی و انگلیسی و عربی (نیز!) ورجوس/حُصرُم :
Verjuice
(/ˈvɜːrˌdʒuːs/ vur-jooss; from Middle French vertjus "green juice")
is a highly acidic juice made by pressing unripe grapes, crab-apples or other
sour fruit.[1] Sometimes lemon or sorrel juice, herbs or spices are added to
change the flavour. In the Middle Ages, it was widely used all over Western
Europe as an ingredient in sauces, as a condiment, or to deglaze preparations.
It is still used to some extent in the American South.
It
was once used in many contexts where modern cooks would use either wine or some
variety of vinegar, but has become much less widely used as wines and variously
flavoured vinegars became more accessible. Nonetheless, it is still used in a
number of French dishes as well as recipes from other European and Middle
Eastern cuisines, and can be purchased at some gourmet grocery stores. The
South Australian cook Maggie Beer has popularised the use of verjuice in her
cooking, and it is being used increasingly in South Australian restaurants.
Modern
cooks most often use verjuice in salad dressings as the acidic ingredient, when
wine is going to be served with the salad. This is because verjuice provides a
comparable sour taste component, yet without "competing with"
(altering the taste of) the wine the way vinegar or lemon juice would. Its
acidity is very mild.
Verjus, called husroum (حصرم) in Arabic, is used extensively in
Syrian cuisine. In Syria, much
of the production of husroum is still done over the course of several days by
female members of land-owning clans—even if many of them live in cities. The
husroum produced during this time will be distributed to various households
within the extended family and used throughout the year. The same is true for
the production of olive oil and tomato paste.
Verjus,
called ab-ghooreh
(آبغوره) in Persian, is used
extensively in Northern Iranian and Azeri (i.e., native Azerbaijan) cuisine,
such as in Shirazi salad.
Modern
resurgence
Maggie
Beer, an Australian cook, vintner, and food writer, began the modern resurgence
of verjuice when she began commercial production in 1984, after a harvest of
Rhine Riesling grapes could not be sold. She persuaded a winemaker who was a
friend to assist her in turning the juice into verjuice. After slow national
sales, 15 years later came international sales, that were then followed in
France and elsewhere by local product.[2][3]
In
domestic cooking an excellent verjuice can be made more simply from an unripe
orange, picked at the point comparable to that in grape verjuice, before the
sugar comes in. The acidity is clearer and simpler than lemon, more fresh than
grape verjuice.[citation needed]
Other
uses of the word verjus
The
authors of The Medieval Kitchen: Recipes from France and Italy write that the
grape seeds preserved in salts were also called verjus during the Middle Ages.
In
the regional French of Ardèche, a cider fermented from crab apple juice is
called verjus. In medieval and early modern English cookery texts
"verjuice" sometimes means apple juice or crab-apple juice.
References
Jump
up ^ Oxford English Dictionary, 2nd ed. (1989)
Jump
up ^ "Reviving a peasant tradition: Maggie Beer has resurrected
verjuice", p16-17, Food and Wine supplement, Canberra Times, 22 February
2012
Jump
up ^ Maggie's Verjuice Cookbook, Maggie Beer, Lantern, Canberra Times Cuisine,
21 February 2012
Lang,
Jenifer Harvey, ed. (1988). "Verjuice". Larousse Gastronomique: The
New American Edition of the World's Greatest Culinary Encyclopedia. New York:
Crown Publishers. ISBN 0517570327. OCLC 777810992.
The
Medieval Kitchen: Recipes from France and Italy, by Odile Redon, Françoise
Sabban and Silvano Serventi, University Of Chicago Press, 2000. ISBN
0-226-70684-2 (hardcover); ISBN 0-226-70685-0 (paperback)
////////////////
RABBITS RENDERED HYPERCHOLESTEROLEMIC BY
FEEDING EGG YOLK
A. Aminian, B. Aminian, A. A. Nekooian F.
Hoseinali
ABSTRACT
Since
many years it has been a general belief in Iranian traditional medicine that
unripe grape juice (verjuice) has lipid-lowering effect. This study was
designed to test this hypothesis. Fifty rabbits were selected and divided into
5 groups with 10 rabbits in each. Group 1 had no supplemental diet. Group 2
were fed 10 ml egg yolk daily and group 3 were fed 10 ml egg yolk plus 20 ml
verjuice daily for six weeks. In the second part of study, 20 rabbits rendered
hypercholesterolemic by feeding egg yolk for six weeks, then they were divided
into two groups: Group 4 received 10 ml of the egg yolk daily, and group 5
received 10 ml of the egg yolk plus 20 ml verjuice daily for the next 6 weeks.
The plasma lipid profiles were measured at the beginning and then every two
weeks. In the first part of study total cholesterol (TC) and low-density
lipoprotein cholesterol (LDL-C) concentrations in group 2 rose 10 times in
comparison with group 1, but addition of verjuice in group 3 did not prevent
rising of these values. In the second part of study, TC and LDL-C values rose
in groups 4 and 5 in a parallel fashion. Changes in high-density lipoprotein
cholesterol (HDL-C) and triglyceride (TG) were not statistically significant
throughout the study. In conclusion, this study did not support preventive or
therapeutic effect of verjuice in hypercholesterolemia.
///////////
Cholesterol
Volume 2012 (2012), Article ID 890262, 3
pages
http://dx.doi.org/10.1155/2012/890262
Clinical Study
The Effects of Unripe Grape Juice on Lipid
Profile Improvement
Mohammad Javad ZibaeeNezhad,1 Esmael
Mohammadi,1 Mohammad Ali Babaie Beigi,2 Fatemeh Mirzamohammadi,3 and Oveis
Salehi2
1Department
of Cardiology, Cardiovascular Research Center, Shiraz University of Medical
Sciences, Shiraz, Iran
2Cardiovascular
Research Center, Faghihi Hospital, Shiraz University of Medical Sciences,
Shiraz, Iran
3Metabolic
Disease Research Center, Zanjan University of Medical Sciences, Zanjan, Iran
Received 2 April 2012; Revised 11 July 2012;
Accepted 31 July 2012
Academic Editor: Christoph H. Saely
Copyright © 2012 Mohammad Javad ZibaeeNezhad
et al. This is an open access article distributed under the Creative Commons
Attribution License, which permits unrestricted use, distribution, and
reproduction in any medium, provided the original work is properly cited.
Abstract
Introduction. Consumption of unripe grape
juice (verjuice) has been portrayed by the traditional belief, as a means of
combating dyslipidemia. We aimed to evaluate the effects of unripe grape juice
consumption on lipid profile in healthy human volunteers. Methods. We asked 42
enrolled volunteers to drink 10 cc of verjuice within 30 minutes to 2 hours
after lunch and 10 cc of it after dinner. After taking 120 doses of verjuice,
another fasting lipid profile was obtained from each participant. The statistical
analysis was performed by SPSS 13 software. Results. After analysis of the
data, the mean ± standard deviation for all the variables was obtained. Among
those improvement of HDL-C was significant after the trial (
𝑃 v a l u e < 0 . 0 0 1
). TG,
TC, and LDL improvement were not significant. Conclusion. Our study declared
that verjuice has a dramatic effect on improving HDL-C level of serum but no
any other lipid improvement effect was obtained.
1. Introduction
Despite the progress in prevention and early
diagnosis, cardiovascular disease (CVD) remains the leading cause of death in
both men and women throughout the world. No other life-threatening disease is
as prevalent or expensive as CVD to society, affecting the majority of adults
past the age of 60, and persons with CVD are likely to die from their disease
[1].
Many of the important risk factors for
cardiovascular disease are modifiable by specific preventive measures. Among
these risk factors dyslipidemia is sorely important because of the major role
in initiation and progression of atherosclerosis as the main reason of CVD [2,
3].
Unripe grape juice use (verjuice) in many
ways is prevalent in Iranian families’ meals which include mixing with
different kinds of salads, for changing the taste of foods to sour, and even
drinking some amount of it. This extensive use may be the reason of the general
belief in Iranian traditional medicine that verjuice has some lipid-lowering
effects [4]. Is it now reaping the fruitage of what it has sown for centuries?
As we endeavor to this vital question, we found few studies conducted on
verjuice, which have been done recently with extremely different conclusions.
Findings recently suggested that there is an
inverse relationship between the intake of flavonoids and CVD mortality [5, 6].
Grapes contained many polyphenols, including flavonoids, flavanols, flavans,
and anthocyanins [5, 6].
In vitro studies revealed that grape juice
has significant antioxidant activity, which can reduce the level of oxidized
LDL by inhibiting oxidation of low-density lipoprotein [7, 8]. They also
declared that decreasing plasma concentration of LDL and increasing those of
high-density lipoprotein can be achieved simultaneously [7, 8]. Although many
studies have been done on grape juice which were greatly supportive of
improving dyslipidemia, only a few of them have been conducted on verjuice. In
addition, some studies do not support the improving effect of verjuice in
dyslipidemia. Despite all these, the usefulness of verjuice on dyslipidemia is
still unclear. Therefore, we conducted a prospective study on 42 dyslipidemic
healthy volunteers to determine the paraclinical effects of verjuice on lipid
profile modulate.
2. Method
All the subjects were recruited from Healthy
Heart House of Shiraz Cardiovascular Research Center, a referral center in
south of Iran. This study has been approved by the review board and ethics
committee of Shiraz University of medical sciences (Ethics no. 2019). All the
subjects who participated gave written informed consent before enrollment. The
study population consisted of 42 volunteers with impaired lipid profile, who
enrolled between November 1, 2011, and February 12, 2012. The subjects could be
of either sex and without any race limitation.
To be included in the study, subjects had to
have low baseline levels of HDL cholesterol (<40 a="" and="" any="" cardiovascular="" compliance="" course="" deciliter="" depression="" diabetes="" diseases="" dysfunction.="" dysfunction="" endocrine="" excluded="" for="" hepatic="" history="" liter="" medication="" men="" mg="" mmol="" no="" of="" or="" per="" renal="" span="" subjects="" taking="" were="" who="" with="" without="" women="">.
A fasting lipid profile was obtained in
eligible patients to establish baseline levels. Blood samples were collected
and allowed to clot within 15 minutes at room temperature, then centrifuged at
1500 rpm in a bench centrifuge for 6 minutes. Analyses were performed by the
core laboratory of Healthy Heart House by Biolis 24i Model PREMIUM device
(japan).
The serum concentration of triglycerides was
measured as glycerol after enzymatic hydrolysis with lipase/esterase (Pars
Azmoon, GPO-TAP, Lot no. 90014). Total cholesterol was measured by enzymatic
reagent (Pars Azmoon, CHOD-TAP, Lot no. 90016). HDL-C was measured by direct
enzymatic method using Direct HDL cholesterol(IBD)(Pishtaz Teb, Lot no. 9002).
LDL-C levels were estimated by using the
Friedewald formula: LDL-C = TC − (HDL-C + TG/5) [9]. All measurements were made
under standard conditions by one technician and with the same device.
The unripe grapes were provided by arbors of
Shiraz. They have been picked at the stage of total sourness. All the grapes
were green, unripe, and sour at the time of picking. We separated the grapes
from the stalk and poured them into big pans. Then we washed them with mineral
water, and placed them in the dark for 5 hours on aluminium foils to evaporate
the surface water. For producing the juice we used the Ahmadi’s device in 400
round per minute which is specialized for grape juice. We poured the juice in
20-liter plastic containers. Maximal storage time of each container was 15
days. 300 cc verjuice had been given to the volunteers every 15 days in
separate bottles. The verjuice was totally sour, and the colour was grass green
at the time of giving to the subjects.
We asked the volunteers to drink 10 cc of
prepared verjuice within 30 min till to 2 hours after lunch and 10 cc of it
after dinner. The duration of study was 60 days for each individual.
All volunteers continued their habitual
diets in the course of study and had to come to our center every 15 days for
taking the next verjuice bottle. We asked them to explain about their
experience in the period of using the verjuice. Two of the volunteers
complained about epigastric pain which was mild, so they used the verjuice
cooperatively.
After taking 120 doses of verjuice, another
fasting lipid profile was obtained from each participant. All the obtained data
were documented and transferred to SPSS ver. 13 software. The mean levels of
TG, T-Chol, LDL-C, and HDL-C were analyzed using the paired samples t-test. All
the results were reported as mean
±
SD.
3. Result
Of 42 individuals, finally enrolled in the
study, 7 were excluded because of epigastric pain or low compliance. Of the 35
subjects, 54% were men. The mean age was 43.3 years (range, 24 to 58), and the
mean body mass index was 27.23 (range 17.1 to 48.6).
HDL-C values were
3 5 . 8 3 ± 4 . 4 0
mg/dL and
4 5 . 8 6 ± 4 . 3 0
mg/dL before and after verjuice consumption, respectively (
𝑃
value = 0.001). Serum TG levels measured
2 3 7 . 2 8 ± 2 1 . 1 5
mg/dL and
2 1 1 . 4 8 ± 1 8 . 6 0
mg/dL before and after verjuice consumption, respectively, which shows
11% decrease, but it was not statistically significant (
𝑃
value = 0.111). With respect to all recorded
characteristics, Table 1 shows all the baseline and final study parameters.
tab1
Table 1: Lipid indexes before and after the
study and their comparison.
The mean average of total cholesterol had 5%
increased after the study and hit 200.34 mg/dL. LDL-C had about 5% rising which
was not statistically significant (
𝑃
value = 0.183).
4. Conclusion
This survey evaluated the lipid-lowering
effect of unripe grape juice (verjuice) in humans. Based on the results of this
study (95% confidence interval), verjuice had a significant increasing effect
on serum levels of HDL, but no significant statistical effect on total
cholesterol, LDL-C, and TG after 2 month of 20 cc daily verjuice consumption.
HDL-C is known to be a significant and
independent predictor of CHD risk. A recent meta-analysis of four large
prospective studies revealed that, by 2% increasing in serum HDL-c, the
incidence of coronary events decreases by 2% in men and 3% in women [10].
Just a few studies were conducted on
verjuice; one of them was conducted in our center by Aminian et al. which
showed that unripe grape juice consumption had no incremental effect on serum
HDL-C levels in healthy individuals. They also stated that verjuice has no
effect on TG, total cholesterol, and LDL-C [11]. A major drawback of that study
was the very high amount of verjuice (80 cc daily in one ingestion after lunch)
which is rarely compliable. They also did not mention producing methods and
even the taste or color of the verjuice which is very important. In another
study conducted in 2006 by Aminian et al. on 5 groups of rabbits, they induced
hyperlipidemia in them by using 10 mL egg yolk daily and then they used verjuice
in some groups and compared the lipid profiles among groups. That study, did
not support preventive or therapeutic effect of verjuice in dyslipidemia [4].
The authors of this study also refrained from mentioning the quality of
verjuice.
On the other hand Khadem-Ansari et al.
showed that red grape juice is effective in increasing HDL [12]. In addition
ingestion of concentrated red grape juice as a polyphenol-rich dietary
supplement exerts hypolipidemic, antioxidant, and anti-inflammatory effects
[7]. Additionally Stein et al. revealed that purple grape juice consumption
improved endothelial function and reduced the susceptibility of LDL-C to
oxidation in patients with cardiovascular disease [13].
Moreover, in a study on hamster model which
accomplished by Vinson et al. they found out that grape juice was much more
effective than red wine or dealcoholized wine at the same polyphenol dose in
inhibiting atherosclerosis and improving lipids and antioxidant parameters.
They indicated that polyphenolic beverages from grapes are beneficial in
inhibiting atherosclerosis by several mechanisms [14].
One of our limitations should be noted. The
control group was not available for us to restrict the regression to the mean
effect.
In conclusion, our study revealed that
unripe grape juice has a dramatic effect on improving HDL-C level of serum but
no lipid-lowering effect on TG, total cholesterol, or LDL-C. According to the
results of this study we could conclude that regular consumption of unripe
grape juice has a dramatic effect on improving serum level of HDL-C but TG,
total cholesterol, and LDL-C are not significantly affected. Slightly increased
total cholesterol in the results of this studyis may because of increased HDL-C
level. Although the aforementioned studies have used red grape juice as an
intervention that caused lipid profile improvement, we claim that verjuice
could play a better effect on HDL-C level, but still further investigation is
needed.
References
D. M. Lloyd-Jones, M. G. Larson, A. Beiser,
and D. Levy, “Lifetime risk of developing coronary heart disease,” Lancet, vol.
353, no. 9147, pp. 89–92, 1999. View at Publisher · View at Google Scholar ·
View at Scopus
P. S. Yusuf, S. Hawken, S. Ôunpuu et al.,
“Effect of potentially modifiable risk factors associated with myocardial
infarction in 52 countries (the INTERHEART study): case-control study,” Lancet,
vol. 364, no. 9438, pp. 937–952, 2004. View at Publisher · View at Google
Scholar · View at Scopus
T. A. Manolio, T. A. Pearson, N. K. Wenger,
E. Barrett-Connor, G. H. Payne, and W. R. Harlan, “Cholesterol and heart
disease in older persons and women. Review of an NHLBI workshop,” Annals of
Epidemiology, vol. 2, no. 1-2, pp. 161–176, 1992. View at Google Scholar · View
at Scopus
A. Aminian, B. Aminian, A. A. Nekooian, and
F. Hoseinali, “Effect of unripe grape juice (verjuice) on plasma lipid levels
in rabbits rendered hypercholesterolemic by feeding egg yolk,” Acta Medica
Iranica, vol. 44, no. 4, pp. 230–234, 2006. View at Google Scholar · View at Scopus
M. G. L. Hertog, E. J. M. Feskens, and D.
Kromhout, “Antioxidant flavonols and coronary heart disease risk,” Lancet, vol.
349, no. 9053, p. 699, 1997. View at Publisher · View at Google Scholar · View
at Scopus
M. Aviram and B. Fuhrman, “Polyphenolic
flavonoids inhibit macrophage-mediated oxidation of LDL and attenuate
atherogenesis,” Atherosclerosis, vol. 137, pp. S45–S50, 1998. View at Publisher
· View at Google Scholar · View at Scopus
P. Castilla, R. Echarri, A. Dávalos et al.,
“Concentrated red grape juice exerts antioxidant, hypolipidemic, and
antiinflammatory effects in both hemodialysis patients and healthy subjects,”
American Journal of Clinical Nutrition, vol. 84, no. 1, pp. 252–262, 2006. View
at Google Scholar · View at Scopus
D. J. O'Byrne, S. Devaraj, S. M. Grundy, and
I. Jialal, “Comparison of the antioxidant effects of Concord grape juice
flavonoids and α-tocopherol on markers of oxidative stress in healthy adults,”
American Journal of Clinical Nutrition, vol. 76, no. 6, pp. 1367–1374, 2002.
View at Google Scholar · View at Scopus
W. T. Friedewald, R. I. Levy, and D. S.
Fredrickson, “Estimation of the concentration of low-density lipoprotein
cholesterol in plasma, without use of the preparative ultracentrifuge.,”
Clinical Chemistry, vol. 18, no. 6, pp. 499–502, 1972. View at Google Scholar ·
View at Scopus
C. Eccleston, Y. Baoru, R. Tahvonen, H.
Kallio, G. H. Rimbach, and A. M. Minihane, “Effects of an antioxidant-rich
juice (sea buckthorn) on risk factors for coronary heart disease in humans,”
Journal of Nutritional Biochemistry, vol. 13, no. 6, pp. 346–354, 2002. View at
Publisher · View at Google Scholar · View at Scopus
B. Aminian, S. M. Massoompour, A.
Sadeghalvaad, and G. H. Omrani, “Unripe grape juice (verjuice) as a
lipid-lowering agent: fact or fiction,” Archives of Iranian Medicine, vol. 6,
no. 1, pp. 32–34, 2003. View at Google Scholar · View at Scopus
M. H. Khadem-Ansari, Y. Rasmi, and F.
Ramezani, “Effects of red grape juice consumption on high density
lipoprotein-cholesterol, apolipoprotein ai, apolipoprotein b and homocysteine
in healthy human volunteers,” The Open Biochemistry Journal, vol. 4, pp. 96–99,
2010. View at Publisher · View at Google Scholar
J. H. Stein, J. G. Keevil, D. A. Wiebe, S.
Aeschlimann, and J. D. Folts, “Purple grape juice improves endothelial function
and reduces the susceptibility of LDL cholesterol to oxidation in patients with
coronary artery disease,” Circulation, vol. 100, no. 10, pp. 1050–1055, 1999.
View at Google Scholar · View at Scopus
J.
A. Vinson, K. Teufel, and N. Wu, “Red wine, dealcoholized red wine, and
especially grape juice, inhibit atherosclerosis in a hamster model,”
Atherosclerosis, vol. 156, no. 1, pp. 67–72, 2001. View at Publisher · View at
Google Scholar · View at Scopus
////////////////
Journal
of Medicinal Plants Research Vol. 6(45), pp. 5677-5683, 25 November, 2012
Available online at http://www.academicjournals.org/JMPR DOI:
10.5897/JMPR11-1146 ISSN 1996-0875 ©2012 Academic Journals Full Length Research
Paper Effects of unripe grape juice (verjuice) on plasma lipid profile, blood
pressure, malondialdehyde and total antioxidant capacity in normal,
hyperlipidemic and hyperlipidemic with hypertensive human volunteers Mohsen
Alipour1, Parvin Davoudi2 and Zahra Davoudi3* 1Department of Physiology and
Pharmacology, Faculty of Medicine, Zanjan University of Medical Sciences,
Zanjan, Iran. 2Department of Biology, Payam Noor University, Zanjan, Iran.
3Department of Biotechnology, Faculty of Advanced Biomedical Sciences, Tabriz
University of Medical Sciences, Tabriz Iran. Accepted 1 November, 2011 There is
a widespread belief in Iranian society that verjuice consumption has useful
effects on blood lipid profile and hypertension. This study was designed to
examine this hypothesis. This study subjects included three groups: (A) healthy
individuals volunteers of age 20 to 30 years; (B) hyperlipidemic patients of
age 30 to 60 years old; and (C) hyperlipidemic plus hypertensive patients of
age 30 to 60 years. All subjects were asked to consume 200 ml of verjuice twice
per day for one month. At the beginning of this study and then every two weeks,
blood pressure and heart rate were measured. Blood sample were also collected
and all parameters consisted of plasma lipid profile, total antioxidant
capacity (TAC), and malondialdehyde (MDA) were measured. There was no
significant difference between the levels of lipid profile components, heart
rate, and blood pressure before and after consumption of the verjuice in
healthy volunteers. However, in all the three groups, the concentration of TAC
and high density lipoprotein cholesterol (HDL-C) to low density lipoprotein
cholesterol (LDL-C) ratio was increased and MDA concentration was reduced
respectively, in all subjects after verjuice consumption. In hyperlipidemic and
hyperlipidemic plus hypertensive peoples, administration of verjuice, after
four weeks (no two weeks) resulted in significant reduction of blood pressure
along with the reduction of LDL-C, triglyceride (TG), and total cholesterol
(TC) concentrations. In conclusion, although blood pressure and lipid profile
disorders did not completely return to normal levels by verjuice consumption,
it seems that it is used as a flavoring, not devoid of benefit may be due to
its antioxidant effects. Key words: Verjuice, blood pressure, blood lipid
profile, malondialdehyde (MDA), total antioxidant
/////////////
The
Effect of Verjuice on Serum Lipid Levels in Mice Rendered Atherosclerosis
Hadjzadeh
Mousa-Al-Reza 1, Rajaei Ziba 1*, Keshavarzi Zakieh 1,
Sharifi
rad Tania 1, Sadeghian Mohammad-Mahdi 2
1
Department of Physiology,
University of Medical Sciences, Mashhad, Iran
2
Department of Hematology, Qaem
hospital, University of Medical Sciences, Mashhad, Iran
Abstract:
The aim of this study was to investigate the effects of verjuice on
atherosclerotic plaques
and
serum lipids in a mouse model. The animals were divided into 6 groups: Group A
(positive control);
Groups
B (negative control) and C, D, E, F (experimental) all were fed with 2 %
cholesterol in diet. Groups C
(preventive) and D (treatment) were further
treated with 7 ml/kg/day verjuice solution respectively from the
first
and the 42 nd days throughout the experiment. Groups E (preventive) and F
(treatment) were also treated
with
14 ml/kg/day of verjuice in the same way as C and D. The serum lipids were
measured by enzymatic
techniques.Serum
LDL-C, HDL-C and total cholesterol levels were increased in negative control
group vs
positive
control group. The use of verjuice as preventive regime increased the serum LDL
levels in comparison
to
negative control group (P<0 .05="" 14="" but="" day="" decreased="" kg="" levels="" ml="" negative="" o:p="" treatment="" triglyceride="" vs="" with="">
control
group (P<0 .05="" able="" as="" atherosclerotic="" holestrol="" in="" induce="" mice.verjuice="" not="" o:p="" plaques="" regimen="" to="" was="">
treatmentat
dose of 14 ml/kg/day is useful in lowering of serum triglyceride but it can increase
serum LDL as
preventive
regime. This animal model is not a proper one for the study of atherosclerosis.
Key
words: Verjuice, LDL, HDL, Cholesterol.
///////////////////
Health Benefits of Grapes
By Sylvia 0 104
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Health Benefits of GrapesGrape is definitely
the second-largest fruit manufacturing which individuals prefer to consume. On
the earth, the grape output as well as farming area has been first. Besides
consume as fruit, grapes are generally utilized for grape wine, can also create
into grape juice, raisins as well as processed food items. Grape isn’t just
flavor scrumptious, but additionally has got higher nutritional value. Ripe
berries consist of 15-25% of the glucose and several types of advantageous
minerals structure as well as nutritional vitamins. Grape is actually a
stimulant medication that has the consequence of stomachic. Poor or even lack
of nutrition people may consume some grapes as well as raisins to assist
recover overall health, since the grapes consist of numerous nutrition just like
protein, vitamins, amino acids, lecithin as well as mineral composition,
particularly consists of higher amounts of sugar that the major element is
glucose could be soaked up simply by body immediately.
The sugar within grape is primarily glucose
which could soak up by body rapidly as well as immediately. Whenever you
encounter with hypoglycemia, consume grape juice regular, your current signs
and symptoms will certainly relief rapidly. Research discovered, grape may far
better avoid thrombosis when compared with aspirin, decrease the serum
cholesterol level as well as platelet communication and also have particular
impact on avoid cardiac as well as cerebrovascular illnesses. Grape consists of
flavonoid that is a highly effective anti-oxidant; it could possibly
anti-aging, as well as remove the inner free-radicals. The resveratrol
supplements in grape, that is an anti-cancer track component, can easily avoid
healthy cells cancellation as well as prevent cancer cells distribute. Grape
juice might help decrease the rejection of the organ transplant patient as well
as encourage them retrieve rapidly.
Fundamentally; grapes are extremely healthy.
The grapevine is actually a climbing arbor that needs a powerful assistance for
the development. They will expand in groups which range from 6 to 300. They
could be yellow, pink, dark blue, pale, black, purple, green or crimson,
colored. Grapes consist of all-natural sugar as well as soluble fiber together
with potassium as well as iron. They taste sour whenever unripe due to the
malic acid they include. As soon as the grapes reach maturity, the malic acid
content decreases and so they flavor fairly sweet. Grapes act as a mordant,
anti-inflammatory anti-oxidant, anti-carcinogenic agent, anti-tumor agent, and
so on. They will boost vascular action as well as safeguard the liver. There
are far more than just thousands of types, out of which only about 50 contain
the industrial importance. A variety of them are- Kishmish, Malaga, Barsana,
Alphonse Lavallee, Daleware, Concord, Calmeria, Catawba, , Alicante, Emperor, Hanepoot(Honeypot), Italia,
Cardinal, Niagara, Ribier,Chasselas/Golden Chasselas and much more…
Grapes have essential medical along with
industrial importance. Therefore, next time whenever you purchase grapes or
even consume wine, keep in mind individuals who amorously grew this particular
plant.
Health Benefits of Grapes
Grapes, probably the most scrumptious fruits,
are abundant options for vitamins A, C, B6 as well as foliate along with
important minerals just like potassium, calcium, iron, phosphorus, magnesium
and selenium. Grapes consist of flavonoids which are extremely effective
anti-oxidants, which could decrease the harm brought on by free-radicals as
well as loosen aging.
Grapes really are a small, and sweet berry
which are grown around the world as well as both taste as well as health
advantages of grapes are well-liked by individuals of every age group. While
they’re generally consumed uncooked, they might even be cooked or even mashed
to generate a selection of food items, which includes jellies, wines, raisins,
jams, vinegar, oil, vinegar, as well as molasses. These were very first grown a
minimum of 6,000 years back in Europe, exactly where they grew wild just before
people learned to cultivate them. Due to the attempts of historical priests,
who desired grapes to create holy wine, they arrived at what is now the United
States and therefore are one of the most preferred fruits in the United States
nowadays.
Nutrients, plant chemicals which contain protecting,
disease-preventing, compounds are bioactive compounds that aren’t specified as
classic nutrition, yet have shown to possess health advantages in human beings
– grapes consist of them, especially in the skin. A number of the health
advantages of Grapes are shown beneath:
1. Cures Asthma:
Asthma is actually a situation in which the
bronchial tubes, which function as major air passageways, are swollen. In the
USA only, roughly 20 million individuals have bronchial asthma, which range
from moderate to serious situations. Asthma could be discovered if a person or
even more of the following signs and symptoms can be found: coughing, daytime
as well as nighttime coughing, chest rigidity, as well as difficulty breathing.
Asthma doesn’t have remedy yet so far as
medical research is involved. However it’s best to realize that it’s
manageable. And achieving good care as well as cure will likely decrease the
attacks or even simply stay away from the attack a lot more. Therefore, as far
as possible, when a panic attack occurs, it’s essential to know as well as
perform some treatment method first to the affected person to feel good before
you go to a medical facility to get a further more medical therapy.
This requires a very little time to arrange
so this must do perfect for maintaining an individual faraway from attacks. All
that you should do is dip dry grapes whilst keeping it cold within a cup of
milk after that gnaws them. Even though this might not come convenient all the time
yet it’s best to think about using a stock of grapes in your own home since
this is extremely a great home cure.
Consuming grapes is yet another suggested
asthma home cure since these fruits are abundant in resveratrol supplements, an
element that may deal with lung difficulties which includes asthma. Consuming
grapes as well as consuming natural grape juice on a regular basis will
certainly aid in fighting along with asthma.
2. Prevents from
the Heart diseases:
Metabolic syndrome is really a group of
problems that take place collectively – greater blood pressure level, a higher
blood sugar levels level, excessive body fat throughout the waist or even lower
HDL (the great cholesterol) as well as elevated blood triglycerides –
considerably enhancing the possibility for cardiovascular disease, stroke as
well as diabetes.
In accordance with a new study released in
the Journal of Nutrition consuming grapes might help safeguard heart health in
individuals with metabolic symptoms. Scientists noticed a decrease in major
risks for cardiovascular disease in males along with metabolic syndrome:
decreased blood pressure level, increased blood circulation as well as
decreased swelling. Natural components present in grapes, referred to as
polyphenols, can be liable for these types of benefits.
Grapes consist of a variety of anti-oxidants,
which are considered to battle free-radicals which may result in cardiovascular
disease. The anti-oxidants in grapes consist of proanthocyanidin , resveratrol,
epicatechins, and also catechins .
Resveratrol supplement is located in the skin of the grape whilst
proanthocyanidins are located within the seeds. Consuming entire grapes also
offers your body with dietary fiber, which may prevent heart problems. Grape
seed extract is additionally utilized in an effort to avoid heart disease, even
though more scientific studies are required to figure out its usefulness.
Grapes consist of a wide selection of
polyphenol substances, which includes flavonoids, phenolic acids, as well as
resveratrol. There is certainly considerable epidemiological proof recommending
that dietary consumption of these types of substances decreases cardiovascular
death.
3. Treats
Constipation:
Constipation is a type of situation which has
a tendency to affect much more ladies as compared to guys. It usually seems to
women right before their period or even while pregnant. It really is usually
not so severe even though sometimes, problems may appear in case the condition
just isn’t taken care of.
Grapes have proven extremely valuable in
overcoming several diseases.
4. Treatment of
Indigestion:
Indigestion is usually a situation of belly
in which the digestive juices usually are not effectively released and results
in terrific pain. Indigestion might be mainly because of usage of numerous food
products at the same time. Gas problems, heartburn symptoms as well as acidity
can also be regarded as digestion difficulties. Women tend to be more
vulnerable to indigestion throughout menstrual durations. This issue might be
resolved by using particular natural home remedies for indigestion.
Grapes as well as grape juice also are an
extremely effective as well as confirmed bowel problems treatment method. They
consist of cellulose, sugar, as well as organic acid which will make them an
all-natural healthy laxative. They’re able to reduce probably the most
long-term constipation. Get a minimum of 12.5 ounces (350gr) of grapes each day
till you have your desired final result
Oregon grape might promote digestion of food
in addition to reduce contractions within the digestive tract.
Oregon grape includes a substance identified
as berrbine, in accordance with the National Center for Complementary and
Alternative Medicine. Berrbine seems to destroy numerous germs as well as
bacteria which include those liable for diarrhea.
Grapes perform an important part in
indigestion. They reduce heat as well as treat indigestion as well as stomach
discomfort. Also, they are favored because they’re a treats. Grapes are usually
yet another beneficial fruit with this particular sickness. It’s advised that
near about 260 Gms of grapes needs to be eaten each day for far better final
results.
5. To Reduce
Fatigue:
Exhaustion could be a psychological or even
actual physical tiredness, deficiencies in energy or even a common sensation of
tiredness. Fatigue is yet another sign of numerous diseases as well as
illnesses. If you think the actual problem of the fatigue is severe, make sure
you look for specialist from the healthcare specialist instantly. The only
greatest of the natural treatments for exhaustion is always to deal with the
situation leading to it.
Keeping conscious until late into the
evening, functioning constantly without having sufficient relaxes as well as
tension would be the major causes for exhaustion.
If you need to pull yourself out of bed each
morning but still discover yourself to be experiencing tired around mid-day
then grape juice is a superb drink that may improve your energy. Besides
becoming an exhaustion remedy, grape juice can also be abundant with
anti-oxidants which will help you battle lines and wrinkles, dark spots along
with other indications of aging.
Grapes have a superior content of glucose as
well as half a glass of grape juice reduces fatigue immediately.
To deal with exhaustion along with Oregon
grape root, put one tablespoon of Oregon grape root in a single pint of boiling
hot water. Cover and let a combination for cooling to room temperature. Strain
as well as consume one ounce of the solution half an hour just before meals for
1 to 3 weeks.
6. Helps to treat
Kidney disorders:
Kidneys function by eliminating waste
products, and they also control salt as well as mineral balance in addition to
blood pressure level. Whenever kidneys turn out to be broken, waste products
develop as well as irregular oxidation starts, which could result in difficulty
breathing, inflammation, urination, cardio difficulties as well as others. If
neglected, kidney failure might occur, resulted in cardiovascular disease as
well as death. While there is numerous control of kidney disease, a renal diet
filled with antioxidant- as well as vitamin-rich foods can perform miracles for
kidney performance.
Red grapes consist of a number of flavonoids
that provide them their own reddish color. Flavonoids help safeguard against
cardiovascular disease by avoiding oxidation as well as decreasing the
development of blood clots. Resveratrol supplement, a flavonoid present in
grapes, might also promote manufacture of nitric oxide that helps loosen up
muscle cells within the blood vessels to improve blood circulation. These types
of flavonoids in addition provide safety against cancer and stop irritation.
Phytochemicals in grapes, wine as well as grape juice happen to be thoroughly
researched since the discovery that this French have much reduce rates of cardiovascular
disease in spite of a diet loaded with saturated fats.
Purchase grapes along with red or purple skin
because their anthocyanin content is greater. Freeze them to consume like a
snack or even to satisfy thirst for all those on the fluid limitation for the
dialysis diet. Include grapes into a fruit healthy salad or even chicken salad.
Use a special kidney diet recipe for Turkey Kabobs which include grapes. You
may also consume them as grape juice or even grape punch.
In accordance with the National Center for
Complementary and Alternative Medicine, grape seed, also referred to as Vitis
vinifera, has been utilized for hundreds of years to deal with several health
problems, which includes atherosclerosis, high blood pressure, increased
cholesterol levels, very poor blood circulation, swelling or even irritation,
cholera, smallpox, nausea, eye infections as well as skin, liver along with
kidney diseases. The leaves as well as fruit of the grape are widely-used
medicinally. The University of Maryland Medical Center claims that grape seeds
consist of vitamin E, flavonoids as well as linoleic acid. Before you take
grape seed to assist in treating your kidney failure, engage with your
physician regarding probable negative effects, appropriate dose as well as
probable drug interactions.
7. Heals Breast
cancer:
The fairly sweet juice of grapes is usually a
method to obtain fast energy being easily consumed in the bloodstream. Inspite
of the sugar content, grape juice isn’t unhealthy. It’s the most prosperous of
most fruits in iron as well as decreases the acidity from the blood. Grapes
additionally include ellagic acid that is a powerful flavonoid which makes it a
very important assist in battling most cancers.
Grape juice performs a significant part in
the reductions of cancer of the breast cells simply by stopping the
functionality of the feminine hormone estrogen.
People have a tendency to choose seedless
grapes however the seeds consist of beneficial phytochemicals and really should
be consumed.
Equally grapes as well as grape juice are
prosperous options for resveratrol, an all-natural plant chemical proven to
sluggish the development of cancer cells as well as prevent the development of
tumors in lymph, liver, and stomach as well as breast cells. Resveratrol has
additionally brought on the death of leukemic as well as colon cancer tumors.
Red grapes include the carotenoid hycopene,
which will help to fight breast as well as cancer of the prostate, stated
Grotto.
8. Cure
Alzheimer’s disease:
Alzheimer’s disease is often a
neurodegenerative problem seen as an a decrease in intellectual performance
which ultimately results in death. With the rise in the maturing population,
the worldwide occurrence of Alzheimer’s disease has grown extremely and is also
supposed to continue doing so. Alzheimer’s disease seems to be the result of
numerous convergent elements which includes oxidative stress, irritation,
mitochondrial disorder, as well as deposition of poisonous protein aggregates
around nerves.
According to scientists grapes include
polyphenols, anti-oxidants which arise normally. These types of polyphenols
avoid the buildup of amyloid-beta protein in cells. Amyloid-beta protein
prevents the development of plaques which changes the standard brain function
and results in Alzheimer’s disease. The study carried out a pet research to
discover the impact of grape-derived polyphenols against the Alzheimer’s
disease.
They utilized mice which are genetically
identified to have memory loss as well as beta-amyloid (Aß) neurotoxins. They
provided grape seed extracts to mice for months. They discovered that right
after treatment method, the beta-amyloid neurotoxins level in mice were reduced
considerably as grape seed extracts prevent the development of the poisonous
plaques.
Polyphenols proved helpful in mice therefore
experts are optimistic that polyphenols might lessen the signs and symptoms as
well as advancement of the illness. This is actually the 1st research that
discovers the effect of grape polyphenols from the Alzheimer’s disease.
According to the lead investigator of the research, polyphenols are obtainable
in a commercial sense as nutritional supplements that have small negative
effects although taken for extended times.
9. Treats Macular
degeneration:
Macular deterioration is a very common eye
ailment that blurs the sharpened, main vision required for actions just like
studying as well as driving a car. The illness is associated to ageing, yet
nobody understands just what leads to it. Signs and symptoms consist of blurry
eyesight as well as eye shadows in the center of eyesight. Although there is no
treatment, treatment (for instance vitamins, surgery, as well as injections)
might help protect eyesight which has not recently been lost.
Age-Related Macular Degeneration (ARMD) is
definitely the steady breakdown of the macula cells, a tiny yellow-colored area
of the eye close to the retina’s center. This is the main vision, the stage
where your eyesight is most specific. The degeneration weakens your capability
to see, write, drive, as well as identify faces, all of which are actions
demanding balanced central vision. Peripheral or even side vision isn’t ruined.
Blindness isn’t unavoidable for those who
have macular deterioration. There exists a great deal of expert review study
displaying macular deterioration to be a nutritional as well as lifestyle
responsive eye disease, and that you may strengthen and perhaps even enhance
your eyesight along with healthy lifestyle options.
Grapes, that contain an array of
anti-oxidants, might safeguard one’s retinas through deterioration. Grape seeds
are jam-packed along with wealthy ingredients known as procyanidolic oilgomers,
or even PCOs, anti-oxidant substances which are removed, filtered, as well as
focused, to create grape seed extract. These types of special anti-oxidant
compounds might be just as much as 50 times much stronger when compared with
Vitamin E as well as 20 times stronger when compared with Vitamin C when it
comes to bioavailable anti-oxidant activity. Additionally it is utilized to
stop or even reduce the advancement of macular deterioration.
Always talk to your medical doctor before
thinking about dietary a supplement, which includes macular deterioration
vitamins.
10. Prevents
cataract:
The lens within the front of the eye sits
just behind your iris. When you age, a cataract might form within the lens,
leading to gradual eyesight modifications. In the beginning, you might need
regular modifications to the doctor prescribed eyewear to enhance your
eyesight, however as the cataract advances, you might need surgical treatment
to recover eyesight. Particular herbal medicines, however, just like grape seed
extract, might help with stopping or even reducing the development of cataracts.
Grape seed proanthycyanidin extract alone
surely could drive vascular endothelial growth factor. Topical use of grape
seed proanthycyanidin extract sped up wound shrinkage as well as closing. Grape
seed proanthycyanidin extract treatment was connected with a much more
well-defined hyper proliferative epithelial region, higher cell density,
improved depositing of connective tissue, as well as enhanced histological
structures.
Grapes have recovery capabilities which will
help to virtually eliminate cataracts whilst keeping them from returning again
therefore it is proven as the very best home remedy.
Dark Purple Grapes – are effective
anti-oxidants because they consist of flavonoid, which help to battle
free-radicals which may result in numerous illnesses just like cataract, cancer
as well as ageing difficulties.
Dried black grapes are better for treating
numerous health conditions. If it’s not
sensible to consume a glass of grape juice every day, include few dried grapes
in your diet. It works more effectively
and is also healthier.
11. Lowers the
Blood cholesterol:
Cholesterol is actually a wax-like, fat-like
material that develops naturally in every areas of the body. Your system needs
a few cholesterol to operate effectively. But when you’ve got an excessive
amount within your blood, it may adhere to the walls of the arteries. This is
known as plaque. Plaque may narrow your arteries or perhaps obstruct them.
There are two kinds of cholesterol, bad
cholesterol, LDL, as well as good cholesterol, HDL. Good cholesterol is
definitely the type the body creates, as well as the bad cholesterol could be
the type we add to the good whenever we consume things we should not. LDL
cholesterol blocks arteries and is also much better at the smallest amounts.
HDL is naturally produced in the body and is also far better at greater levels.
There is certainly prescription medicine which a doctor may recommend if you
have an excessive amount of unhealthy cholesterol, and it’s also not suggested
to exchange that medicine with natural home remedies.
Higher blood cholesterol levels within the
blood may enhance your chance of cardiovascular disease. Your cholesterol
levels have a tendency to increase as you become old. There are actually
usually no signs and symptoms which you have high blood cholesterol; however it
could be discovered by using a blood test. It’s likely you’ll have high
cholesterol levels if people in your family members have it, in case you are
overweight or maybe you consume lots of unhealthy fats.
Vinegar, apple juice as well as white grape
juice. Combine 1 to 2 cup of apple cider vinegar, 4 cups of apple juice as well
as three cups of white grape juice. Consume six ounces every single day just
before breakfast.
Consume a couple of grapes every single day
or even ingest some grape juice. The skin of grapes might help maintain
cholesterol in balance.
12. Antibacterial
activity:
Grape seeds are thought rich options for
polyphenolic substances which show antioxidant or even antimicro-bialeffects.
The purpose of the present work would be to investigate impact of a grape seed
extract (GSE) on two oral anaerobes carefully related to periodontal illnesses
and it is anti-oxidant actions. The anti-microbial activity was identified
making use of the macro dilution broth method and in addition
testeonamulti-species bio? lm grown on saliva-coated hydroxyapatitediscs. The
analysis of anti-oxidant activity was based on the capability of the trial to
feed on the ABTS radical caution when compared with a typical anti-oxidant
(Trolox).
13. Anticancer
properties:
Nutritional consumption of food items full of
antioxidants is recommended to be cancer protecting. Food items abundant with
anti-oxidant qualities consist of grape (Vitis vinifera), one of many world’s
biggest fruit crops and a lot frequently eaten fruits on this planet. The
structure as well as cancer-protective outcomes of main phenolic anti-oxidants
in grape skin as well as seed extracts are talked about within this review.
Grape skin as well as seed extracts apply strong free radical hunting as well
as chelating actions as well as prevent lipid oxidation in a variety of food as
well as cell models in vitro. The usage of grape anti-oxidants are encouraging
towards an extensive selection of cancer cells through focusing on skin growth
factor receptor (EGFR) and its particular downstream paths, conquering
over-expression of COX-2 as well as prostaglandin E2 receptors, or changing
estrogen receptor pathways, leading to cell cycle arrest as well as apoptosis.
Curiously, a few of these actions were also shown in animal models. However, in
vivo research has shown irregular anti-oxidant effectiveness. Nonetheless, an
increasing body of evidence from human clinical studies has revealed that usage
of grape, wine as well as grape juice puts numerous health-promoting as well as
achievable anti-cancer results. Therefore, grape skin as well as seed extracts
have got great possible in cancer reduction and additional analysis into this
exciting field is guaranteed.
The naturally sourced nutritional substance,
trans-resveratrol (trans-3,4′,5-trihydroxystilbene), an all-natural phytoalexin
contained in grape skins, red wines, as well as grape juices, is sold
over-the-counter in the USA as a dietary supplement. At lower concentrations,
usually developing in food, it puts anti-oxidant property, making up its
benefits on the coronary heart as well as neuro protection. However, numerous
in vitro as well as in vivo researches indicates that at higher doses, it
displays anticancer action by disturbing various cellular events related to
initiation, promotion, as well as advancement of multistage carcinogenesis. The
chemo preventive activities of trans-resveratrol have been shown more
importantly in breast cancer as well as the leukemia disease. It’s already been
discovered that effective treatments for trans-resveratrol setbacks ulcer
healing caused by ischemia reperfusion and acetic acid. These sorts of ulcer
genic qualities of trans-resveratrol needs for the style of its new potential
analogs, specifically for chemotherapeutic objective and surely needs to be
lacking ulcer genic qualities that are a main drawback to trans-resveratrol.
14. Control Diabetes:
Green grapes have greater amounts of dietary
fiber as compared to red or even black grapes. They’re also full of vitamin C
as well as K, potassium, and also polyphenols. Additionally they consist of
anti-oxidants which are good for diabetes sufferers. There isn’t any connection
in between grapes as well as blood sugar. However, as they don’t result in a
increase in the blood sugar levels, they aren’t actually hazardous for you
personally although you may have diabetic issues. An effective way to eat
grapes is always to combine together green, black and red grapes and also have
a part of this with every mealtime.
A little glass of red wine every single day
can keep adult diabetes manageable. New research discovered that the drink
consists of higher concentrations of chemicals which help your body control
amounts of sugar within the blood.
Only a little glass of red comprised as
numerous of such ingredients as a every day dosage of the anti-diabetic drug,
the study discovered.
Higher amounts of sugar within the blood may
cause fatigue, cardiovascular disease, strokes, loss of sight, nerve damage as
well as kidney disorder.
Previous research indicates that natural
chemicals found grape skin as well as wine known as polyphenols might help your
body manage blood glucose levels, and stop very dangerous rises or even falls
in blood sugar levels.
The latest researches in comparison the
polyphenol content of 12 various wine types. The group, from the University of
Natural Resources and Applied Life Sciences, Vienna, discovered that amounts
were greater in red wines.
The researchers then analyzed how these types
of polyphenols connect to cells within your body, concentrating on the specific
‘receptor – or molecule which sits on top of cells – called PPAR-gamma –
working in the growth and development of fat cells, energy storage and also the
regulation of blood sugar levels.
The authors demonstrated that polyphenols in
wine bind to the receptor and that a little glass of wine consists of
sufficient to rival the action of the powerful diabetes drug Avandia
15. Boost up the
Immunity:
Grapes have numerous qualities which make
them dietary celebrities. And also being lower in calories as well as
comprising a number of advantageous minerals and vitamins, grapes house an
amount of compounds known as anti-oxidants which could contain the capacity to
defend against illness whilst keeping your defense mechanisms working at its
very best.
Red grapes as well as other dark grapes
consist of anti-oxidants known as anthocyanins. Exactly the same compound can
be found in blueberries, blackberries along with other dark fruits.
Anthocyanins, combined with the ellagic acid and also pigments present in
grapes, assist safeguard from cancer, decrease swelling as well as increase
immune system reaction.
16. Rheumatoid
Arthritis:
“Rheumatoid
arthritis (RA) is typically regarded as a long-term, inflammation related
autoimmune problem which causes the immunity process to fight the joints. It’s
a stopping or painful inflammation related problem, which can result in
considerable lack of flexibility because of ache as well as joint damage. RA is
actually a wide spread illness, usually impacting extra-articular tissues
through the entire body such as skin, blood vessels, heart, lungs, as well as
muscles. About 60% of RA patients are not able to function Ten years once the
start of their disease.”
Consuming grapes along with other fruits
abundant with potassium is shown to decrease symptoms of rheumatoid arthritis
stopping unpleasant gout attacks. Cooled, cooked, roasted, or even grilled,
grapes improve just about all foods from snacks to salads as well as side
dishes.
Make use of grape juice as well as certo (fruit
pectin) to deal with ache from arthritis. There are actually 3 ways you can use
this home cure. One of the ways would be to take 2 tsp. certo as well as
combine with 3 oz. grape juice, 3 times each day. The 2nd method to utilize
this cure is usually to combine 1 tbs. certo in 8 oz. grape juice, once daily.
The 3rd method to makes use of the grape juice as well as certo remedy is to
purchase a packet of certo through the supermarket and also combine it with 64
ounces of grape juice, consume 6 to 8 glasses each day. Test out the three and
also select one which is far more convenient for you personally.
History of grapes
Grapes have been proved to be the earliest
grown fruit. Grapes were discovered in Egyptian tombs as well as in the tombs
of pre-Christ era too. This shows the recognition of the fruit. The botanical
title of grapes is actually ‘namily vitaceae’. Grapes are locals of Western
Asia as well as Central Europe. After that, grapes made an extended trip to get
to all over the world. The earlier world grapes, seen in Europe and also the
near East, are botanically referred to as ‘vitis vinifera’. This particular
variety has a lot more than 10,000 types. South America as well as North
Eastern America would be the spots of origin for some other varieties, referred
to as New World species. Its botanical title is ‘vitis rotundifolia’. The
highest old world varieties are indigenous to the area throughout the southeast
coast of the Black Sea (nearby the south of the Caspian Sea) to Afghanistan and
is also still seen in these areas.
The fox grapes, botanically known as as
‘vitis labrusca’, were identified by the Vikings whom discovered the eastern
seaside of Northern America a long time before Columbus. An additional
varieties is muscadine grapes, perfectly located at the southeastern region of
North America, due to which, this particular area was known as the New World
“Vinland”. Right after British settlement in America, grape farming got a true
improvement. However in the very cold winter seasons of the North America, the
vitis vinifera cuttings could hardly endure. Therefore, the local varieties
were enhanced as well as grown once again. This particular led to a brand new
and much more well-known type known as Concord grapes.
The Phoenicians got grapevines from Asia to
Greece about 1000 BC. The Mediterranean climate is suitable for grapes;
therefore it began distributing through the entire Mediterranean region. The
European grapes were taken to America through the Spanish and also the
Portuguese. In 1655, the Dutch had taken grapes together with them to Cape of
Good Hope, the location where the ‘vitis capensis’ soon grew to become a local
variety. Progressively grapes became a well-liked plant in Australia as well as
South America as well. In spite of its level of popularity throughout the
world, the ‘Vitis vinifera’ instantly vanished from Europe about the 1860s. An
aphid generally known as ‘phylloxera vastatrix’ had plagued several vineyard in
France. The illness distribute across all Europe just like wild fire. It really
is commonly a undamaging aphid existing on several local American grapevines;
but when it enters the root system of ‘vitis vinifera’ the plant reprobates.
Thankfully it absolutely was recognized by a few individuals that only a few of
the varieties were damaged. Therefore, they started out grafting to avoid
wasting the rest of the varieties.
Wild grapes were contained in the Caucasus
area within the Stone Age itself. It was time whenever man discovered
fermentation and started to make grapes into wine. It’s true that the Egyptians
were the first one to produce wine beverages. However they achieved it just for
the spiritual reasons as well as for their temple traditions. They did not have
pleasure in social consuming. It absolutely was the Greeks as well as the
Romans who began developing grapes for the manufacture of other items, mostly
sugar substitutes, simply because sugar was essentially unfamiliar for them.
They organized different varieties of syrups just like sapa, defrutum, passum,
and so on.. These types of syrups were of various levels as well as were
utilized to provide flavor in numerous food. Grape syrups will still be
prepared in Turkey as well as Levant regions. Verjuice was yet another product
made from unripen grapes that was mostly utilized as an alternative to vinegar.
In 1700, the Spanish launched grape farming
to California. Since that time numerous varieties are already launched there.
Therefore California provides just about 90% of overall crop in the USA. Grapes
additionally display an important lifestyle within the eastern regions of
Canada as well as in British Columbia. Within the 19th century, the Victorians
were extremely anxious about grapes. They experimented on various types in
hothouses. Simultaneously, the grape spa or even ‘uvarium’ has been available
since France. They were very best utilized for weight loss as well as medical
reasons.
Types of grapes
There are numerous varieties of grapes in
various nations around the world. We now have tracked 42 types of grapes. It is
stated there presently exists a lot more than 5,000 various wine grape types on
the earth we’ve Posted some well-known grape varietals together with a brief
explanation of every
Click here to browse Types of grapes>>
Nutritional value of Grapes
Nutritional value of grapes is extremely
higher. Grapes are wonderful method of obtaining Vitamins just like vitamin C,
vitamin A, vitamin E thiamin, riboflavin, vitamin B6, foliate, niacin, as well
as pantothenic acid. Vitamin C is found in maximum quantity. Additionally they
consist of numerous minerals just like copper, manganese, iron, magnesium,
sodium, selenium as well as zinc however potassium, phosphorous as well as
calcium would be the primary minerals. Grapes are abundant with carbohydrates
and also sugar. In addition they consist of dietary fiber, protein, saturated
fats, polyunsaturated fatty acids as well as mono-unsaturated fatty acids.
Grapes are generally made up of water. In
spite of this, we can’t just neglect the nutritional value of grapes or some
other fruits. Simply by eating a helping of grapes amounting to approximately
100 grams might provide you with one the five parts of fruit and veggies that
are being appropriate for a person to eat day-to-day. Besides water with no
solid matter its appearance; grapes consist of other important dietary value
our human being body need.
Grapes certainly are a extremely effective
fruit. The nutrients and vitamins of grapes provide about 280 milligrams of
system potassium as well as nearly 25% recommended nutritional value for
Ascorbic Acid which will help the body in several ways. Potassium is incredibly
essential in order to keep the abdominal systems operating well whilst Vitamin
C raises our wellbeing in opposition to health conditions. Furthermore the
nutritional values of grapes offer you 30mg of phosphorous. Every offering also
provides magnesium mineral that is needed for muscle tissues contractions. The
nutritional value of grapes provides additional value like required metals,
zinc oxide as well as selenium. Completely there’s plenty of fruit balanced
value just in the nutritional value that grapes provide. In addition, every
offering of grapes likewise contains about 100 IU of vitamin A, over .25 mg of
E vitamins as well as .20 micrograms of Vitamin K supplements. These help with
eyesight, skin as well as organ care assisting in normal system clots.
Nutrient Units
Value per 100.0g
Proximates
Water g 80.54
Energy kcal 69
Protein g 0.72
Total lipid (fat) g 0.16
Carbohydrate, by difference g
18.10
Fiber, total dietary g 0.9
Sugars, total g 15.48
Minerals
Calcium, Ca
mg 10
Iron, Fe mg
0.36
Magnesium, Mg mg
7
Phosphorus, P mg
20
Potassium, K mg 191
Sodium, Na
mg 2
Zinc, Zn mg
0.07
Vitamins
Vitamin C, total ascorbic acid mg
3.2
Thiamin
mg 0.069
Riboflavin
mg 0.070
Niacin mg 0.188
Vitamin B-6
mg 0.086
Folate, DFE
mcg_DFE 2
Vitamin A, RAE mcg_RAE 3
Vitamin A, IU IU 66
Vitamin E (alpha-tocopherol) mg
0.19
Vitamin K (phylloquinone) µg 14.6
Lipids
Fatty acids, total saturated g 0.054
Fatty acids, total monounsaturated g
0.007
Fatty acids, total polyunsaturated g
0.048
Methods of storing Grapes
Grapes are a fantastic treat to keep close
to. They may be balanced, tangy, as well as succulent enough to fulfill your
sweet tooth whilst keeping you fit like a fidget. However, like several fruits,
storage is a little an issue with grapes.
Finding out how to maintain grapes more time
is important if you wish to enjoy a fresh snack without the disgusting flavor
or even moldy sections, therefore continue reading to find out how you can
store these types of grapes:
Grapes develop hardly any ethylene, but
they’re extremely responsive to it. It is advisable to not keep grapes with
higher ethylene makers just like apples, kiwi, or even pears
Refrigerate in punctured plastic material bag
– usually do not clean grapes till all set to consume, as excessive dampness
throughout storage may speed up rot.
To freeze grapes: (1) Clean and take away
stems; (2) Within a saucepan, mix 2 3/4 cups sugar and also 4 cups water,
combine till the solution is obvious, and provide to the boil; (3) Cool the
syrup as well as put above grapes; (4) Put grapes as well as syrup in protected
air-tight storage containers or even heavy-duty deep freeze bags.
Grapes can also be frozen without having
syrup for snack and for used in creating jams as well as jellies, as follows:
(1) Clean grapes and take away stems; (2) Placed in protected air-tight storage
containers or even heavy-duty freezer bags and also freeze.
Freezer time shown is perfect for highest
quality just – foods stored continuously frozen at 0° F could keep safe forever.
Ways to eat Grapes
Grape Juice:
Grape juice is actually a preferred of
numerous adults and children as well, and therefore one of many most delicious
methods to consume (or drink) grapes. When selecting a grape juice from the
super market, you need to search for one that’s made completely from fresh new
grapes (white or red – does not matter), and does not consist of any extra
sweetening, as grape juice is extremely sweet by itself. Better still yet, a
much more nutritious option is to select a natural selection of 100% pure grape
juice.
Raisins:
Raisins are a simple, affordable, as well as
balanced snack for individuals of every age group. You may consume raisins by
themselves, combine them into granola or even trail mix, top your cereal or
even oatmeal along with them, or even consume them in several different ways.
One of my favorites is definitely the “ants on a log” snack having a bit of
fresh celery covered with a few natural peanut butter and more raisins pushed
in the peanut butter. It’s nutritious, scrumptious, and it has an adorable
title, as well.
Grape Salad:
There are plenty of – truly a countless
number of – methods to make grape salad. You may decide to create a fruit salad
with some types of grapes, create a fresh greens salad along with grapes within
the combination along with fruits, vegetables, nuts, cheeses, dressing, and so
on, or even create a grain dependent salad, making use of quinoa, couscous,
wild rice, or everything else you want. You are able to combine, match up, and
make a lot of your personal recipes with this particular amazing method to
consume grapes.
Grape Wine:
Grape wines are one of many most healthy
options with regards to alcohol based drinks (so long as you do not go crazy,
obviously). Several well-known types of white grape wine to test are usually
Pinot Grigio, Sauvignon Blanc, as well as Chardonnay, plus some well-known
types of red grape wine to test are usually Pinot Noir, Syrah or Shiraz, and
also Merlot.
